Autoimmune rheumatic diseases are conditions arising from an abnormal immune system activation and characterised by multi-visceral involvement. Although many progresses have been done, in the last years, in managing these patients, clinical remission may be reached in less than 50% of patients and a precision medicine, in this field, is still far away. The overarching aim of this workshop is to understand if stratification of patients, enrolled in trials designed to assess the efficacy of specific drugs or spontaneous studies may improve the knowledge about the therapeutic response and patients satisfaction. Seven immune-mediated diseases will be evaluated: rheumatoid arthritis, systemic lupus erythematosus, primary Sjogren’s syndrome, systemic sclerosis, spondyloarthritis, adult-onset Still’s disease. The methodology of this meeting is Delphi Technique-based aimed at producing, starting from the results of a systematic review of available literature, a set of statements summarising the consensus among the Experts.